Not known Details About sodium phenobarbital solubility
Not known Details About sodium phenobarbital solubility
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Drug interactions: Most studies of clinically considerable drug interactions happening with the barbiturates have involved phenobarbital.
pentobarbital will lower the extent or effect of lorlatinib by influencing hepatic/intestinal enzyme CYP3A4 metabolism.
pentobarbital will minimize the extent or effect of exemestane by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep an eye on. For sufferers getting exemestane with a strong CYP3A4 inducer the suggested dose of exemestane is 50 mg daily after a food.
pentobarbital will decrease the extent or effect of bazedoxifene/conjugated estrogens by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Monitor.
pentobarbital will reduce the extent or effect of buprenorphine by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep track of.
pentobarbital increases toxicity of ifosfamide by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on. CYP3A4 inducers may perhaps enhance the metabolism of ifosfamide to its Energetic alkylating metabolites.
pentobarbital will minimize the extent or effect of abiraterone by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on.
pentobarbital will lessen the extent or effect of estropipate by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch.
pentobarbital will lessen the extent or effect of nitrendipine by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Minimal/Importance Not known.
Estradiol, estrone, progesterone and other steroidal hormones: Pretreatment with or concurrent administration of phenobarbital may possibly lessen the effect of estradiol by increasing its metabolism.
pentobarbital will decrease the level or effect of losartan by affecting hepatic enzyme CYP2C9/10 metabolism. Slight/Significance Mysterious.
fentanyl transmucosal and pentobarbital both of those maximize sedation. Avoid or Use Alternate Drug. Restrict use to clients for whom alternative procedure choices are insufficient
This mechanism is probably with the induction of hepatic microsomal enzymes that metabolize the antibiotic. If phenobarbital and doxycycline are administered concurrently, the clinical response to doxycycline ought to be monitored closely.
pentobarbital will lessen the extent or effect of cilostazol by influencing hepatic/intestinal enzyme here CYP3A4 metabolism. Use Warning/Observe.